Fan Liu
What is referred to as “MudPit” here is not “a pit of mud” but a technique in the mass spectrometry field which 
stands for “multi-dimensional protein identification technology”, a very powerful approach that has been widely used since the year of its inception in 2001.
Many efficient technologies have been developed to reveal global behaviors of DNA (genome) and RNA (transcriptome), such as DNA-DNA interactions (through chromatin conformation capture on chip) and global gene expression (through transcriptome sequencing). However, the systematic study of proteins (proteome) lags behind the analytical DNA and RNA analysis.