Traditional light microscopes are not able to resolve images small enough to explore the details of cells. One of the techniques used to investigate nanoscale samples is atomic force microscopy (AFM). AFM uses a very fine tip (atoms in diameter) attached to a cantilever to “feel” the surface of a sample. This method is ideal for measuring microfabrication, like silicon chips, but traditionally was too harsh on living organisms. Yet, advancements in the technology and new techniques have opened new possibilities for exploring the fine details of microbes.